Boc-2-(trifluoromethyl)-L-β-phenylalanine, (R)-3-(Boc-amino)-3-[2-(trifluoromethyl)phenyl]propionic acid - Names and Identifiers
Boc-2-(trifluoromethyl)-L-β-phenylalanine, (R)-3-(Boc-amino)-3-[2-(trifluoromethyl)phenyl]propionic acid - Physico-chemical Properties
Molecular Formula | C15H18F3NO4
|
Molar Mass | 333.3 |
Density | 1.269±0.06 g/cm3(Predicted) |
Boling Point | 426.1±45.0 °C(Predicted) |
pKa | 4.20±0.10(Predicted) |
Storage Condition | 2-8°C |
Boc-2-(trifluoromethyl)-L-β-phenylalanine, (R)-3-(Boc-amino)-3-[2-(trifluoromethyl)phenyl]propionic acid - Risk and Safety
Boc-2-(trifluoromethyl)-L-β-phenylalanine, (R)-3-(Boc-amino)-3-[2-(trifluoromethyl)phenyl]propionic acid - Introduction
Boc-R-3-Amino-3-(2-trifluoromethyl-phenyl)-propionic acid is an organic compound whose structural formula is:
The properties of this compound are as follows:
-Appearance: Usually white to off-white solid
-Formula: C- H-F. NO.
-Molecular weight: 307.27g/mol
Boc-R-3-amino -3-(2-trifluoromethylphenyl) propionic acid uses:
This compound is commonly used as a protecting group and an intermediate in organic synthesis. It is a common amino acid protecting group that protects amino acid side chains in synthetic peptide and protein chemistry. In addition, it can also be used as an intermediate of drugs, which has certain application potential in the field of medicine.
Preparation of Boc-R-3-amino -3-(2-trifluoromethylphenyl) propionic acid:
A common preparation method is obtained by esterification of 3-amino -3-(2-trifluoromethylphenyl) propionic acid with Boc acid (tert-butoxycarbonyl). The specific steps include: first reacting 3-amino -3-(2-trifluoromethylphenyl) propionic acid with an amine base to obtain a corresponding amine; then reacting the amine with a corresponding acid, introducing a Boc protecting group through an esterification reaction, and finally obtaining Boc-R-3-amino -3-(2-trifluoromethylphenyl) propionic acid.
Last Update:2024-04-09 02:00:49